Thursday, August 14, 2014

Methylation of the DNA to inhibit high transposons

In an article published online in Genome Biology , researchers from the University of California at Los Angeles (UCLA) and Parma in Italy were interested in the epigenetic processes that could control these transposons. Thus, methylation of DNA is an epigenetic modification in which a methyl group is added to the nucleotide cytosine . Involved in many process control genetic , it can inactivate transposons. The DNA methylation exist in animals, plants and fungi, but was lost in some invertebrates , which can lead to phenotypes as abnormal developmental problems or cancers .

Methylation of the DNA to inhibit high transposons

Scientists measured the proportion of methylated cytosine in the genome of the black truffle at different stages of development: ascocarp (at which point the truffle is harvested), the mycelium (the fungus grows in the soil after germination of a spore) and ectomycorrhizae (stage symbiosis between the fungus and the roots).

The methylation patterns were very similar in all three stages. The rate of cytosine methylation was especially high (44%), with a preference for GC sites and transposons large (over 1500 bp).

http://androidstars.newsvine.com/_news/2014/08/05/25184437-tomorrow-rosetta-will-add-a-chapter-to-the-saga-of-the-comet-hunting
http://androidgeek.ucoz.com/blog/alloy_simulated_on_computer_from_quantum_physics/2014-08-06-21
http://carmiell.blogspot.com/2014/08/video-3d-reconstruction-of-comet-rosetta.html

This work may explain the relationship between DNA methylation and intraspecific variability, but also the properties organoleptic fungus: aromas and color . Matteo Pellegrini, one of the authors of the article, the black truffle would use epigenetic processes to control its genes and adapt to changes in its environment. "This methylation reversible may increase the plasticity of the genome of the nose, which would allow it to adapt to its environment. Because truffles lives below ground and has no active system spore dispersal, it may require plasticity to adapt to sudden changes in their environment, " Has he commented.

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